Effects of a Structured, Modified Mediterranean Dietary Intervention After Liver Transplantation
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to study the effects of a structured Mediterranean dietary program on prevention of weight gain, promotion of heart health and prevention of fatty liver disease after liver transplantation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adult patients ≥ 18 years of age undergoing primary liver transplant
• Ascites-adjusted BMI ≥ 25 kg/m2
• Acceptable graft function (total bilirubin level \< 5 mg/dL and doppler ultrasound with patent hepatic artery, hepatic veins and portal veins)
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
Mohammad Qasim Khan, M.B.B.S.
khan.mohammadqasim@mayo.edu
507-284-3917
Backup
Kymberly Watt, MD
watt.kymberly@mayo.edu
507-266-1586
Time Frame
Start Date: 2021-01-19
Estimated Completion Date: 2026-07
Participants
Target number of participants: 80
Treatments
No_intervention: Standard of Care Group
Subjects will participate in a standardized Transplant Nutrition class between day 21-40 as per institutional protocol and will be counseled as per the Mayo Clinic standard of care vis a vis dietary intervention, standard aerobic and resistance exercise recommendations (consistent with AASLD guidelines) and other lifestyle interventions.
Experimental: Behavioral: Structured Modified Mediterranean Diet
Subjects will participate in a one-on-one counselling session with a dietician, as opposed to attending the standardized Transplant Nutrition class. Counselling will be provided on the elements of the modified Mediterranean diet which emphasizes consumption of fruits, vegetables, whole grains, beans and nuts, in addition to low salt, moderate amounts of lean protein (primarily fish and poultry) in addition to low to moderate quantities of monounsaturated fats.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic